Antibacterial Activity of Some Isolated Endophytic Fungi from Menthe Viridis

The aim of the present study was to isolate, identify and observe antibacterial activity of the endophytic fungi against some pathogenic bacteria as well as to optimize various parameters for maximum production of antibacterial bioactive compounds. Endophytic fungi were isolated from Menthe viridis collected from Khamariya, Jabalpur M.P. (India). Screening of endophytic fungi for in-vitro antibacterial activity against six pathogenic bacteria i.e. Bacillus subtilis, Streptococcus pyogenes Escherichia coli, Klebsiella pneumoniae, Salmonella typhimurium and Enterococcus sp. was seen by agar well diffusion method. The potent fungus was optimized for suitable media, pH, temperature and salt concentration to obtain the maximum production of bioactive compound. A total eight endophytic fungi Aspergillus fumigatus, Aspergillus niger, Fusarium solani, Aspergillus repens, Alterneria alternata, Alternaria sp., Phoma hedericola and Fusarium oxysporum were isolated and evaluated with respect to their antibacterial activity against six pathogenic bacteria. In the present study, the fungal strain Fusarium oxysporum produced potent antibacterial bioactive compounds and may be commercially browbeaten for the development of novel drugs.